产品货号:
Z22650
中文名称:
p28/IL27抗体
英文名称:
Anti-p28/IL27 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-p28/IL27 Antibody |
指标别名 | IL 27;IL 27 A;IL 27 subunit alpha;IL 27A;IL27;IL-27;IL27 A;IL27A;IL27p28;IL30;interleukin 27;Interleukin 27 subunit alpha;p28 |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | ELISA,WB,ICC |
基因名称 | IL27 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Anti-IL-27 antibody was raised against a peptide corresponding to 16 amino acids near the amino terminus of human IL-27.The immunogen is located within the first 50 amino acids of IL-27. |
计算分子量 | 27kDa |
成分 | IL-27 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | IL-27 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Like interleukin-23 (IL-23),IL-27 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines.It exists as a heterodimer composed of the p40-related protein EBI3 and an IL-12 p35-related protein termed p28.IL-27 is produced after activation by antigen-presenting cells and induces proliferation of na?ve but not memory CD4+ T-cells.It acts by binding to its receptor WSX-1 and gp130 which results in the activation of a Jak/STAT signaling cascade,suggesting the IL-27 is involved in the regulation of immune processes.It has been suggested that IL-27 can also be used as a therapeutic agent against cancer as it can also induce tumor-specific anti-tumor activity mediated through CD8+ T-cells,IFN-gamma,and T-bet. |
Uniprot ID | Q8NEV9 |
基因名全称 | Interleukin 27 |
蛋白名全称 | Interleukin 27 |
推荐稀释比 | WB:0.5 ~ 4μg/mL;ICC:10μg/mL.Antibody validated:Western Blot in human and mouse samples;Immunocytochemistry in mouse samples.All other applications and species not yet tested. |
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